Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-nucleus RNA sequencing defines adipose tissue subpopulations that contribute to Tibetan pig cold adaptation

24 Apr 2025

Abstract excerpt

Thermogenic beige adipocyte displays a remarkable ability in mammals to adapt to cold environments, but the underlying cellular mechanisms remain unclear, especially in pigs that lack functional UCP1. Multilocular beige adipocytes were observed in both Tibetan pigs (cold-tolerant) and Bama pigs (cold-sensitive) after short-term cold exposure (4 ℃ for 3 days). Through single-nucleus RNA sequencing of adipose...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Cancer-related molecular mechanisms research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40275312
DOI: 10.1186/s12915-025-02211-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-nucleus RNA sequencing defines adipose tissue subpopulations that contribute to Tibetan pig cold adaptationPMID 40275312Read ↗

The Role of β3-Adrenergic Receptors in Cold-Induced Beige Adipocyte Production in PigsSemantic proximity Read ↗

Shifts of Immune Cell Populations Differ in Response to Different Effectors of Beige Remodeling of Adipose TissueSemantic proximity Read ↗

Cold-Induced Reprogramming of Subcutaneous White Adipose Tissue Assessed by Single-Cell and Single-Nucleus RNA SequencingSemantic proximity Read ↗

Multidimensional Single-Nuclei RNA-Seq Reconstruction of Adipose Tissue Reveals Adipocyte Plasticity Underlying Thermogenic ResponseSemantic proximity Read ↗

snRNA-seq of adipose tissues reveals the potential cellular and molecular mechanisms of cold and disease resistance in Mongolian cattleSemantic proximity Read ↗

Single-nucleus transcriptomes reveal the underlying mechanisms of dynamic whitening in thermogenic adipose tissue in goatsSemantic proximity Read ↗

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogrammingSemantic proximity Read ↗

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogrammingSemantic proximity Read ↗

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogrammingSemantic proximity Read ↗

Epigenomic features associated with body temperature stabilize tissues during cold exposure in cold-resistant pigsSemantic proximity Read ↗

A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcriptionSemantic proximity Read ↗

Molecular and cellular regulation of thermogenic fatSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.