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TNIK’s emerging role in cancer, metabolism, and age-related diseases

21 May 2024

Abstract excerpt

Traf2- and Nck-interacting kinase (TNIK) has emerged as a key regulator of pathological metabolic signaling in several diseases and is a promising drug target. Originally studied for its role in cell migration and proliferation, TNIK possesses several newly identified functions that drive the pathogenesis of multiple diseases. Specifically, we evaluate TNIK's newfound roles in cancer, metabolic disorders, and...

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PMID: 38777670
DOI: 10.1016/j.tips.2024.04.010

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