Article

Primary bovine embryonic fibroblasts support seasonal influenza A virus infection and demonstrate variable fitness of HPAI H5N1

2025-07-27

Abstract excerpt

The emergence of highly pathogenic avian influenza (HPAI) H5N1 (clade 2.3.4.4b, genotype B3.13) in dairy cattle presents substantial challenges to the agricultural sector and public health. Mechanistic studies of infection and transmission in cattle have proven difficult due to animal handling restrictions as well as limited availability of established cell culture models. Primary B ovin e E mbryonic F ibroblas...

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Literature Corpus work: e983af21-a3a5-5176-be40-67ab62229c43
DOI: 10.1101/2025.07.26.666677

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