Article

Nutrient landscape shapes the genetic diversification of the human gut commensal <i>Bacteroides thetaiotaomicron</i>

2025-06-24

Abstract excerpt

Bacteroides thetaiotaomicron is a prominent member of the human gut microbiome that has evolved a suite of polysaccharide utilization loci (PUL) to break down a range of diet- and host-derived glycans. To gain insight into the evolution of this bacterium on ecologically meaningful time scales, we carried out an in vitro evolution study in which B. thetaiotaomicron was cultivated on media of different carbohydrat...

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Literature Corpus work: e968cdeb-cffb-54b6-8db0-8fafd099e58b
DOI: 10.1101/2025.06.24.661248

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