Article

Bone Morphogenetic Protein Pathway Modulates Parkinson’s Disease Genetic Risk and Promotes Motor Recovery

2026-06-11

Abstract excerpt

Progress toward disease-modifying Parkinson’s disease (PD) therapies is hindered by limited understanding of pathogenic drivers and lack of therapies that restore the damaged dopaminergic (DA) neurons driving motor deficits. We investigated the role of the bone morphogenetic protein (BMP) pathway in PD using common and rare genetic variants across large-scale datasets. Single-variant analyses identified nominal as...

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Literature Corpus work: e940d171-3d5a-54ce-b351-2ee0a2e68a98
DOI: 10.64898/2026.06.08.730818

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