Article

MET signaling drives acquired resistance to erdafitinib in muscle-invasive bladder cancer cells

2025-07-02

Abstract excerpt

<title>Abstract</title> <p> Muscle-invasive bladder cancer (MIBC) is an aggressive malignancy with high recurrence and poor survival, accounting for the majority of bladder cancer–related deaths. A subset of MIBC harbors <italic>FGFR1</italic> amplification or overexpression, associated with increased proliferation and poor prognosis. Although the pan-FGFR inhibitor erdafitinib has demonstrated clinical benefi...

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Literature Corpus work: e938b146-6632-5a53-8bd3-670649329d61
DOI: 10.21203/rs.3.rs-6348619/v1

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