Article

Identification and Validation of a PEX5-Dependent Signature for Prognostic Prediction in Glioma

2023-09-26

Abstract excerpt

Gliomas, the most prevalent and lethal form of brain cancer, are known to exhibit metabolic alterations that facilitate tumor growth, invasion, and resistance to therapies. Peroxisomes, essential organelles responsible for fatty acid oxidation and reactive oxygen species (ROS) homeostasis, rely on the receptor PEX5 for the import of metabolic enzymes into their matrix. However, the prognostic significance of PEX5...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e92df7d9-914e-57a6-9a87-c78b39ac3347
DOI: 10.20944/preprints202309.1748.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification and Validation of a PEX5-Dependent Signature for Prognostic Prediction in GliomaDOI 10.20944/preprints202309.1748.v1Read

Identification and Validation of a PEX5-Dependent Signature for Prognostic Prediction in Glioma.Semantic proximity Read

Identification of COX5B as a novel biomarker in high-grade glioma patientsSemantic proximity Read

Novel prognostic features and personalized treatment strategies for mitochondria-related genes in glioma patientsSemantic proximity Read

SLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in gliomaSemantic proximity Read

SLC1A5 Enhances Malignant Phenotypes Through Modulating Ferroptosis Status and Immune Microenvironment in GliomaSemantic proximity Read

A Prognostic lncRNA Signature Associated with Lipid Metabolism in GliomaSemantic proximity Read

Integrated genomic, transcriptomic, and epigenetic analyses identify a leukotriene synthesis-related M2 macrophage gene signature that predicts prognosis and treatment vulnerability in gliomasSemantic proximity Read

FABP5 enhances malignancies of lower‐grade gliomas via canonical activation of NF‐κB signalingSemantic proximity Read

FABP5 enhances malignancies of lower-grade gliomas via canonical activation of NF-κB signalingSemantic proximity Read

Key Genes Are Associated with the Prognosis of Glioma, and Melittin Can Regulate the Expression of These Genes in Glioma U87 CellsSemantic proximity Read

Comprehensive analysis of the expression levels and prognostic values of PRDX family genes in glioma.Semantic proximity Read

A pan-cancer analysis has uncovered CCDC58, a mitochondrial gene associated with epilepsy, as a potential prognostic and immunotherapeutic biomarker for various cancer types, including gliomasSemantic proximity Read