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SLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in glioma

24 Dec 2022

Abstract excerpt

Glioma is the most common type of primary malignant tumor in the central nervous system with limited treatment satisfaction. Finding new therapeutic targets has remained a major challenge. Ferroptosis is a novel and distinct type of programmed cell death, playing a regulatory role in the progression of tumors. However, the role of ferroptosis or ferroptosis-related genes (FRGs) in glioma progression has not been...

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PMID: 36566214
DOI: 10.1038/s41419-022-05526-w

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