Article

New insights and updated guidelines for epigenome-wide association studies

2014-11-19

Abstract excerpt

Epigenetic dysregulation in disease is increasingly studied as a potential mediator of pathophysiology. The epigenetic events are believed to occur in somatic cells, but the limited changes of DNA methylation in studies to date indicate that only subsets of the cells tested undergo epigenetic dysregulation. The recognition of this subpopulation effect indicates the need for care in design and execution of epigenom...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e92dc196-8071-5032-a7e9-596cbd22b138
DOI: 10.1016/j.nepig.2014.10.004

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

New insights and updated guidelines for epigenome-wide association studiesDOI 10.1016/j.nepig.2014.10.004Read

Considerations for Design and Analysis of DNA Methylation Studies.Semantic proximity Read

Guidance for the design and analysis of cell-type specific epigenetic epidemiology studiesSemantic proximity Read

Epigenome mapping in normal and disease States.Semantic proximity Read

Epigenome-wide association studies for common human diseases.Semantic proximity Read

Epigenome-wide Association Studies and the Interpretation of Disease -Omics.Semantic proximity Read

Epigenetics at the epicenter of modern medicine.Semantic proximity Read

Genome-scale approaches to the epigenetics of common human disease.Semantic proximity Read

Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and diseaseSemantic proximity Read

Laboratory methods to decipher epigenetic signatures: a comparative reviewSemantic proximity Read

Great expectations - Epigenetics and the meandering path from bench to bedside.Semantic proximity Read

Clinical promise and applications of epigenetic biomarkersSemantic proximity Read

Evaluating the role of genetic variation in the epigenome in health and disease.Semantic proximity Read