Article

<i>NLGN3</i> autism variants have distinct functional impact on synapses and sleep behavior in <i>Drosophila</i>

2026-03-30

Abstract excerpt

Neuroligin-3 (NLGN3) was first identified as a risk gene associated with autism spectrum disorder (ASD). The initial variant, p.R451C, associating NLGN3 with ASD has been heavily investigated, yet little is known about the functional consequences of other NLGN3 variants. Furthermore, while most of the identified variants are present in males with maternally inherited variants from unaffected mothers, several de...

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Literature Corpus work: e9243240-7a9b-54f0-b275-27ad63104245
DOI: 10.64898/2026.03.26.714389

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