Article
Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis
2015-06-03
Abstract excerpt
We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV), and hepatitis C virus (HCV) from four human blood samples by MinION nanopore sequencing coupled to a newly developed, web-based pipeline for real-time bioinformatics analysis on a computational server or laptop(MetaPORE). At titers ranging from 107-108 copies per milliliter, reads to EBOV from two patients with acute hemorrh...
Topics
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- Bacteriophages and microbial interactions
- Genomics and Phylogenetic Studies
- Infective Endocarditis Diagnosis and Management
- Insect symbiosis and bacterial influences
- Mosquito-borne diseases and control
- Viral gastroenteritis research and epidemiology
- Viral Infections and Outbreaks Research
- Viral Infections and Vectors
Identifiers and source
- Literature Corpus work
- e8f16c8f-95fc-547b-8aad-aafa1c0afab8
- DOI
- 10.1101/020420
