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Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis

23 Sept 2015

Abstract excerpt

We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV), and hepatitis C virus (HCV) from four human blood samples by MinION nanopore sequencing coupled to a newly developed, web-based pipeline for real-time bioinformatics analysis on a computational server or laptop (MetaPORE). At titers ranging from 10(7)-10(8) copies per milliliter, reads to EBOV from two patients with acute...

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PMID: 26416663
DOI: 10.1186/s13073-015-0220-9

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