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Nanopore metagenomic sequencing for detection and characterization of SARS-CoV-2 in clinical samples

18 Nov 2021

Abstract excerpt

OBJECTIVES: The COVID-19 pandemic has underscored the need for rapid novel diagnostic strategies. Metagenomic Next-Generation Sequencing (mNGS) may allow for the detection of pathogens that can be missed in targeted assays. The goal of this study was to assess the performance of nanopore-based Sequence-Independent Single Primer Amplification (SISPA) for the detection and characterization of SARS-CoV-2. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34793508
DOI: 10.1371/journal.pone.0259712

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