Back to search

Article

Emodin Inhibits the Growth and Invasion and Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via PI3K/AKT/mTOR and Wnt/β-catenin Pathway

2021-09-02

Abstract excerpt

<h4>Background: </h4> Previous studies reported that emodin extracted from Rheum palmatum L. exerts antiproliferation and anti metastatic effects in a variety of human cancer types. However, the role of emodin in hepatocellular carcinoma (HCC) remain unknown. <h4>Methods: </h4>: EdU and colony formation assays were performed to evaluate the effects of emodin on proliferation. The mobility capacities of HCC treated...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e8e75bc3-49e0-55aa-aa93-a22cbdccf4a1
DOI
10.21203/rs.3.rs-826021/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Emodin Inhibits the Growth and Invasion and Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via PI3K/AKT/mTOR and Wnt/β-catenin PathwayDOI 10.21203/rs.3.rs-826021/v1
Regulating Epithelial-Mesenchymal Transition and Cancer Metastasis: The Multifaceted Role of EmodinSemantic proximity
The Mechanism of Aloe-emodin in the Treatment of Colon Cancer based on Network Pharmacological AnalysisSemantic proximity
Beauvericin Induces Mitochondrial Apoptosis and Attenuates EMT-Associated Phenotypes and Angiogenic Signaling in Colorectal Cancer Cells In Vitro.Semantic proximity
Elaeagnus angustifolia Plant Extract Induces Apoptosis via P53 and Signal Transducer and Activator of Transcription 3 Signaling Pathways in Triple-Negative Breast Cancer CellsSemantic proximity
Curcumin regulates cell proliferation and invasion of human triple-negative breast cancer Hs578T cells via the mTOR signaling pathwaySemantic proximity
Oleanolic Acid Inhibits the Proliferation and Invasion of U251Glioma Cells and Promotes their Apoptosis through the IKK-β, MAPK3, and MAPK4 Signaling PathwaySemantic proximity
Erianin Induces Apoptosis and Autophagy in Oral Squamous Cell Carcinoma CellsSemantic proximity
Anthocyanidins inhibit epithelial–mesenchymal transition through a TGFβ/Smad2 signaling pathway in glioblastoma cellsSemantic proximity
Exploring the mechanism of Naringenin in the treatment of hepatocellular carcinoma based on mRNA sequencing and experimental validationSemantic proximity
Effect of Ursolic Acid, Selenium Nanoparticles, and Their Combination on the Metastasis-Associated Gene Expression in MDA-MB-231 Breast Cancer Cells: In-vitro StudySemantic proximity
Cannabigerol potentiates rivoceranib in hepatocellular carcinoma through a receptor-independent ER stress–calcium program that collapses the E2F1–FOXM1 axisSemantic proximity
Ginsenoside Compound K Inhibits the Proliferation, Migration and Invasion of Eca109 cell via VEGF-A/Pi3k/Akt PathwaySemantic proximity
Select a neighboring publication to make it the new centre.