Article

Curcumin regulates cell proliferation and invasion of human triple-negative breast cancer Hs578T cells via the mTOR signaling pathway

2023-05-04

Abstract excerpt

<title>Abstract</title> <p>Curcumin, a polyphenolic compound isolated from the herb turmeric rhizome, is of interest for its potent biological activity, and in vitro studies have shown that it has broad anticancer activity. We investigated the impact of curcumin on the proliferation, migration, and invasion of TNBC Hs578T cells and further explored the underlying mechanisms. It was confirmed that the proliferatio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1fe9e07a-af70-561c-aabc-66bcf1736a17
DOI: 10.21203/rs.3.rs-2647719/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Curcumin regulates cell proliferation and invasion of human triple-negative breast cancer Hs578T cells via the mTOR signaling pathwayDOI 10.21203/rs.3.rs-2647719/v1Read

Curcumin suppresses metastasis of triple-negative breast cancer cells by modulating EMT signaling pathways: An integrated study of bioinformatics analysisSemantic proximity Read

TP53R175H mutation promotes breast cancer cell proliferation through CORO1A-P38 MAPK pathway regulation.Semantic proximity Read

Anti‐colorectal cancer targets of resveratrol and biological molecular mechanism: Analyses of network pharmacology, human and experimental dataSemantic proximity Read

Shikonin inhibits migration and invasion of triple-negative breast cancer cells by suppressing epithelial-mesenchymal transition via miR-17-5p/PTEN/Akt pathwaySemantic proximity Read

Curcumin Enhances ATG3-Dependent Autophagy and Inhibits Metastasis in Cervical CarcinomaSemantic proximity Read

Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancerSemantic proximity Read

RhoBTB3 Regulates Proliferation and Invasion of Breast Cancer Cells via Col1A1Semantic proximity Read

Shikonin inhibits migration and invasion of triple-negative breast cancer cells by suppressing epithelial-mesenchymal transition via miR-17-5p/PTEN/Akt pathwaySemantic proximity Read

The LncRNA RMST-miR-4295-ITPR1 axis: a key mechanism in regulating autophagy in triple-negative breast cancer cellsSemantic proximity Read

Integrated Network Pharmacology Reveal New Key Curcumin-Binding Targets in Triple-Negative Breast CancerSemantic proximity Read

In Vivo CRISPR Screens Identify RhoV as a Pro-Metastasis Factor of Triple-Negative Breast CancerSemantic proximity Read

Triptonide Effectively Inhibits Triple-Negative Breast Cancer Metastasis Through Concurrent Degradation Of Twist1 And Notch1 OncoproteinsSemantic proximity Read