Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pan-cancer analysis reveals tumor-associated macrophage communication in the tumor microenvironment

10 May 2021

Abstract excerpt

BACKGROUND: Tumor-associated macrophages (TAMs) are abundant in the tumor microenvironment (TME). However, their contribution to the immunosuppressive status of the TME remains unclear. METHODS: We integrated single-cell sequencing and transcriptome data from different tumor types to uncover the molecular features of TAMs. In vitro experiments and prospective clinical tests confirmed the results of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Immune cells in cancer
Share to Phagocytosis and Immune Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33971970
DOI: 10.1186/s40164-021-00226-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pan-cancer analysis reveals tumor-associated macrophage communication in the tumor microenvironmentPMID 33971970Read ↗

At the Interface of Tumor-Associated Macrophages and Fibroblasts: Immune-Suppressive Networks and Emerging Exploitable TargetsSemantic proximity Read ↗

Tumor-associated macrophages: functional diversity, clinical significance, and open questions.Semantic proximity Read ↗

Pan-cancer tumor classification by a holistic tumor microenvironment atlasSemantic proximity Read ↗

Redefining Tumor-Associated Macrophage Subpopulations and Functions in the Tumor Microenvironment.Semantic proximity Read ↗

Single-Cell Analysis of the Pan-Cancer Immune Microenvironment and scTIME PortalSemantic proximity Read ↗

Tumor-associated macrophage clusters linked to immunotherapy in a pan-cancer censusSemantic proximity Read ↗

Intercellular Molecular Crosstalk Networks within Invasive and Immunosuppressive Tumor Microenvironment Subtypes Associated with Clinical Outcomes in Four Cancer TypesSemantic proximity Read ↗

Tissue‐Resident Macrophages in Cancer: Friend or Foe?Semantic proximity Read ↗

Systematic analysis and experimental validation of the prognostic and immunological effects of SPP1 tumor-associated macrophage features in colorectal cancerSemantic proximity Read ↗

Distinct Tumor-TAM Interactions in IDH-Stratified Glioma Microenvironments unveiled by Single-Cell and Spatial TranscriptomicsSemantic proximity Read ↗

Cancer‐Associated Fibroblasts: Heterogeneity, Cancer Pathogenesis, and Therapeutic TargetsSemantic proximity Read ↗

Distinct tumor-TAM interactions in IDH-stratified glioma microenvironments unveiled by single-cell and spatial transcriptomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.