Article

Microglia modulate concussion biomarkers and cognitive recovery in male mice

2025-05-07

Abstract excerpt

There is a critical unmet need for concussion biomarkers that predict cognitive recovery. Existing TBI biomarkers largely capture acute cellular damage rather than the multicellular repair processes that determine long-term outcome, and whether microglia causally shape divergent trajectories remains unclear. Here, we used PLX5622 to deplete microglia and other CSF1R-dependent myeloid cells in a male mouse model co...

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Literature Corpus work: e8c993a3-26b3-5039-918b-90dccf7853de
DOI: 10.1101/2025.05.01.651070

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