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Article

Real-World Safety Profile of Baricitinib and the Structural Basis of Viral Reactivation: A Multi-Disciplinary Analysis

2026-03-19

Abstract excerpt

<title>Abstract</title> <p>Background Baricitinib, a JAK1/2 inhibitor for rheumatoid arthritis, carries boxed warnings for infections and thrombosis. However, its real-world adverse event profile and the molecular mechanisms driving specific risks—particularly herpes zoster (HZ)—remain incompletely understood. We integrated pharmacovigilance and systems biology to characterize baricitinib’s safety profile and el...

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Literature Corpus work
e89a9fb5-c887-54d0-ab71-1278ad8a09fb
DOI
10.21203/rs.3.rs-9085036/v1
Open publication

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