Back to search

Article

Large-scale antibody reactome profiling identifies herpesvirus-autoantigen associations underlying chronic diseases

2026-04-13

Abstract excerpt

<title>Abstract</title> <p>Herpesviruses infect nearly all humans and have long been implicated in autoimmune and chronic diseases, yet their immune interactions with host proteins have not been systematically characterized at population scale. We profiled immunoglobulin G reactivities to >4,600 herpesvirus peptides and >15,000 human proteins using multiplexed protein display in two Mass General Brigham Biobank c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
00dce595-96fc-5aa5-8e3a-cf8b23076a89
DOI
10.21203/rs.3.rs-9371123/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Large-scale antibody reactome profiling identifies herpesvirus-autoantigen associations underlying chronic diseasesDOI 10.21203/rs.3.rs-9371123/v1
The landscape of host genetic factors involved in immune response to common viral infectionsSemantic proximity
An Autoantigen-ome from HS-Sultan B-Lymphoblasts Offers a Molecular Map for Investigating Autoimmune Sequelae of COVID-19Semantic proximity
The landscape of host genetic factors involved in immune response to common viral infections.Semantic proximity
Deconvoluting virome-wide antibody epitope reactivity profilesSemantic proximity
Predominance of Distinct Autoantibodies in Response to SARS-CoV-2 InfectionSemantic proximity
Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody.Semantic proximity
Deciphering the IgG Idiotype Network Through Proteomic Analysis of Potential Targets in SARS ‐ CoV ‐2‐Induced Immune ResponsesSemantic proximity
Human Autoantigen Atlas: Searching for the Hallmarks of AutoantigensSemantic proximity
An autoantigen profile of human A549 lung cells reveals viral and host etiologic molecular attributes of autoimmunity in COVID-19Semantic proximity
An Autoantigen Profile of Human A549 Lung Cells Reveals Viral and Host Etiologic Molecular Attributes of Autoimmunity in COVID-19Semantic proximity
Differential human antibody repertoires following Zika infection and the implications for serodiagnostics and disease outcomeSemantic proximity
Comprehensive serological profiling of human populations using a synthetic human viromeSemantic proximity
Select a neighboring publication to make it the new centre.