Article

Stochastic Modeling of BMP Heterodimer-Receptor Interactions Shows Emergence of Low-Pass Filtering Behavior

2025-10-17

Abstract excerpt

In developing tissues, signal transduction from morphogen gradients conveys positional information to cells, resulting in cell specification and differentiation. One such morphogen is bone morphogenetic protein (BMP), of the TGF-β superfamily, whose signaling network is highly conserved across many species. In Danio rerio (zebrafish), this signaling pathway directs dorsoventral axis formation during early embryog...

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Literature Corpus work: 630b3895-7b13-5fa5-b79e-2934fa1aee3e
DOI: 10.1101/2025.10.17.677951

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