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Article

The role of glucocorticoid receptor nuclear trafficking in oxidative stress induced corticosteroid insensitivity

2013-01-01

Abstract excerpt

Corticosteroids are widely used in the treatment of chronic inflammatory diseases. However, in patients with chronic obstructive pulmonary disease (COPD), cystic fibrosis and a subset of patients with severe asthma, corticosteroids fail to improve the underlying inflammation. Recent advances in the cellular and molecular basis of the pathology in asthma and COPD have revealed several biological targets that may co...

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Identifiers and source

Literature Corpus work
e85968f3-d393-5091-b9cc-06cfbf0562f0
DOI
10.25560/17818
Open publication

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