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Article

Refractory asthma: mechanisms, targets, and therapy

29 Apr 2014

Abstract excerpt

Asthma is a common medical condition affecting 300 million people worldwide. Airway inflammation, smooth muscle bronchoconstriction leading to airflow obstruction, and mucous hypersecretion are clinical hallmarks of asthma. The NHLBI Expert Panel Report 3 recommends inhaled corticosteroids (ICS) for patients with moderate to severe persistent asthma. Inhaled corticosteroids (ICS) target gene transcription through...

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PMID: 24773466
DOI: 10.1111/all.12412

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