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Article

Pro-asthmatic cytokines regulate unliganded and ligand-dependent glucocorticoid receptor signaling in airway smooth muscle.

PloS one - 1 Jan 2013

Hu Aihua, Josephson Maureen B, Diener Barry L, Nino Gustavo, Xu Shuyun, Paranjape Chinmay, Orange Jordan S, Grunstein Michael M

Abstract excerpt

To elucidate the regulation of glucocorticoid receptor (GR) signaling under pro-asthmatic conditions, cultured human airway smooth muscle (HASM) cells were treated with proinflammatory cytokines or GR ligands alone and in combination, and then examined for induced changes in ligand-dependent and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Glucocorticoid

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Source

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Identifiers

PMID: 23593222
DOI: 10.1371/journal.pone.0060452
PMCID: PMC3617099

Genes

MED14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23593222-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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