Article
Glucocorticoid resistance in inflammatory diseases.
Lancet (London, England) - 30 May 2009
Barnes Peter J, Adcock Ian M
Abstract excerpt
Glucocorticoid resistance or insensitivity is a major barrier to the treatment of several common inflammatory diseases-including chronic obstructive pulmonary disease and acute respiratory distress syndrome; it is also an issue for some patients with asthma, rheumatoid arthritis, and inflammatory bowel disease. Several molecular mechanisms of glucocorticoid resistance have now been identified, including...
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