Article

The bacterial amyloids phenol soluble modulins from <i>Staphylococcus aureus</i> catalyze alpha-synuclein aggregation

2021-03-10

Abstract excerpt

Aggregated α-synuclein (α-syn) is the main constituent of Lewy bodies, the main pathological hallmark of Parkinson’s disease (PD). Environmental factors are thought to be potential triggers capable of initiating the aggregation of the otherwise monomeric α-syn. Braak’s seminal work redirected attention to the intestine and recent reports of dysbiosis have highlighted the potential causative role that the microbiom...

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Literature Corpus work: e83afcae-4057-5113-8012-c5db1d8be616
DOI: 10.1101/2021.03.10.434765

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