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The menace within: bacterial amyloids as a trigger for autoimmune and neurodegenerative diseases

11 Apr 2024

Abstract excerpt

Bacteria are known to produce amyloids, proteins characterized by a conserved cross-beta sheet structure, which exhibit structural and functional similarities to human amyloids. The deposition of human amyloids into fibrillar plaques within organs is closely linked to several debilitating human diseases, including Alzheimer’s and Parkinson’s disease. Recently, bacterial amyloids have garnered significant...

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PMID: 38608623
DOI: 10.1016/j.mib.2024.102473

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