Article

Single OCT4 gene introduced into human bone-marrow derived mesenchymal stromal cells can generate putative iPS cells with the potential to differentiate into CD34+ hematopoietic progenitor cells ex vivo

2020-03-19

Abstract excerpt

<h4>Background: </h4> The ex vivo production of CD34+ hematopoietic progenitor cells from human bone-marrow mesenchymal stromal cells derived induced pluipotent stem cells (iPSCs) could serve as a feasible way to study patient-specific hematological disease from the perspective of hematopoietic differentiation. Different studies using virus-based or virus-free methods to reprogramming somatic cells into iPSCs by u...

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Literature Corpus work: e817b21f-b797-5989-9196-5fdf8164207f
DOI: 10.21203/rs.3.rs-17882/v1

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