Article

RiVIERA-beta: Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases

2016-06-16

Abstract excerpt

Genome wide association studies (GWAS) provide a powerful approach for uncovering disease-associated variants in human, but fine-mapping the causal variants remains a challenge. This is partly remedied by prioritization of disease-associated variants that overlap GWAS-enriched epigenomic annotations. Here, we introduce a new Bayesian model RiVIERA-beta ( Ri sk V ariant I nference using E pigenomic R eference...

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Literature Corpus work: e7f24352-a4ad-5fba-8e18-dc39a88f23b9
DOI: 10.1101/059329

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