Article

Sarcoglycan A Mutation in Miniature Dachshund Dogs Causes Limb Girdle Muscular Dystrophy 2D

2020-09-28

Abstract excerpt

<title>Abstract</title> <p>BackgroundA cohort of related miniature dachshund dogs with exercise intolerance, stiff gait, dysphagia, myoglobinuria and markedly elevated serum creatine kinase activities were identified. MethodsMuscle biopsy histopathology, immunofluorescence microscopy, and western blotting, were combined to identify the specific pathologic phenotype of the myopathy, and whole genome SNP array geno...

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Literature Corpus work: e7a5dbb7-24d4-5eb0-9838-9829e7d43648
DOI: 10.21203/rs.3.rs-82758/v1

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