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Article

Congenital muscular dystrophy in a dog with a LAMA2 gene deletion.

Journal of veterinary internal medicine - 1 Jan 2022

Shelton G Diane, Minor Katie M, Thomovsky Stephanie, Guo Ling T, Friedenberg Steven G, Cullen Jonah N, Mickelson James R

Abstract excerpt

A 2-year-old female spayed dog was presented with a chronic history of short-strided gait and inability to completely open the jaw. Clinical signs were present since the dog was adopted from a humane society at a few months of age. Serum creatine kinase activity was abnormally high. Neurological examination, electromyography, muscle biopsies with immunofluorescent staining, and whole genome sequencing (WGS) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34854126
DOI: 10.1111/jvim.16330
PMCID: PMC8783360

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