Article
LncRNA BRE-AS1 Regulates the JAK2/STAT3-mediated Inflammatory Activation via the miR-30b-5p/SOC3 Axis in THP-1 cells
2024-03-11
Abstract excerpt
Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators in numerous biological processes, including macrophage-mediated inflammatory responses, which play a critical role in the progress of diverse diseases. This study focuses on the regulatory function of lncRNA BRE-AS1 in modulating the inflammatory activation of monocytes/macrophages. Employing the THP-1 cell line as a model, we demonstrate that lipop...
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Identifiers and source
- Literature Corpus work
- e77c3194-7899-5dfc-ae92-19798e8f9566
- DOI
- 10.1101/2024.03.06.583653
