Back to search

Article

LncRNA BRE-AS1 Regulates the JAK2/STAT3-mediated Inflammatory Activation via the miR-30b-5p/SOC3 Axis in THP-1 cells

2024-03-22

Abstract excerpt

<title>Abstract</title> <p>Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators in numerous biological processes, including macrophage-mediated inflammatory responses, which play a critical role in the progress of diverse diseases. This study focuses on the regulatory function of lncRNA BRE-AS1 in modulating the inflammatory activation of monocytes/macrophages. Employing the THP-1 cell line as a mode...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a9dce076-f6f0-5ed5-83b0-e9012e9e5ce7
DOI
10.21203/rs.3.rs-4020613/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
LncRNA BRE-AS1 Regulates the JAK2/STAT3-mediated Inflammatory Activation via the miR-30b-5p/SOC3 Axis in THP-1 cellsDOI 10.21203/rs.3.rs-4020613/v1
LncRNA BRE-AS1 Regulates the JAK2/STAT3-mediated Inflammatory Activation via the miR-30b-5p/SOC3 Axis in THP-1 cellsSemantic proximity
LncRNA BRE-AS1 regulates the JAK2/STAT3-mediated inflammatory activation via the miR-30b-5p/SOC3 axis in THP-1 cellsSemantic proximity
MicroRNA-27a-5p downregulates the expression of proinflammatory cytokines in lipopolysaccharide-stimulated human dental pulp cells via NF-κB signaling pathwaySemantic proximity
Opposite effects of miR-155 in the initial and later stages of lipopolysaccharide (LPS)-induced inflammatory responseSemantic proximity
Exosomal miR‑301a‑3p of airway epithelial cells regulates macrophage polarization and promotes lung injury via the GATA1 pathway in acute respiratory distress syndromeSemantic proximity
Analysis of differentially expressed long noncoding RNAs in LPS-induced human HMC3 microglial cellsSemantic proximity
Alternative Splicing And Global Transcriptome Changes Associated With LPS Stimulation In Human Peripheral Blood Mononuclear CellsSemantic proximity
The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microgliaSemantic proximity
LncRNAs Affecting NF-κB-Mediated Macrophage Inflammation Are Potential Therapeutic Targets in Human DiseasesSemantic proximity
Long Noncoding RNA SNHG4 Remits Lipopolysaccharide‐Engendered Inflammatory Lung Damage by Inhibiting METTL3 - Mediated m6A Level of STAT2 mRNASemantic proximity
The BET inhibitor attenuates the inflammatory response and cell migration in human microglial HMC3 cell lineSemantic proximity
Role of Stat3 in Lipopolysaccharide-Induced IL-10 Gene ExpressionSemantic proximity
Select a neighboring publication to make it the new centre.