Article

DapB is a conserved target for tackling antimicrobial resistance in Mycobacterium tuberculosis

2025-07-10

Abstract excerpt

Tuberculosis (TB) remains a major global health issue, with growing challenges posed by drug resistance, highlighting the urgent need to identify new drug targets. This study examines the conservation pattern of the dapB gene, which encodes Dihydrodipicolinate reductase (DapB), a key enzyme in the lysine biosynthesis pathway of Mycobacterium tuberculosis ( Mtb ), a pathway absent in humans. The dapB gene was a...

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Literature Corpus work: e779307d-f00c-553f-bc02-97c5cd7e81ab
DOI: 10.22541/au.175217236.64777388/v1

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