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Article

DapB is a conserved target for tackling antimicrobial resistance in Mycobacterium tuberculosis.

Journal of biomolecular structure & dynamics - 1 May 2026

Mahajan Pratik, Gor Hetarth, Joshi Manali, Nema Vijay

Abstract excerpt

Tuberculosis (TB) remains a major global health issue, with growing challenges posed by drug resistance, highlighting the urgent need to identify new drug targets. This study examines the conservation pattern of the dapB gene, which encodes Dihydrodipicolinate reductase (DapB), a key enzyme in the lysine biosynthesis pathway of Mycobacterium tuberculosis (Mtb), a pathway absent in humans. The dapB gene was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41197090
DOI: 10.1080/07391102.2025.2581074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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