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Article

A 5′ UTR ‐mediated translational efficiency mechanism inhibits the C andida albicans morphological transition

7 Mar 2014

Abstract excerpt

While virulence properties of Candida albicans, the most commonly isolated human fungal pathogen, are controlled by transcriptional and post-translational mechanisms, considerably little is known about the role of post-transcriptional, and particularly translational, mechanisms. We demonstrate that UME6, a key filament-specific transcriptional regulator whose expression level is sufficient to determine C....

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PMID: 24601998
DOI: 10.1111/mmi.12576

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