The deSUMOylase SPF2 and the cohesin regulators SGO2 and CTF18 suppress crossovers near centromeres.

doi:10.1038/s41477-026-02329-1

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Article

The deSUMOylase SPF2 and the cohesin regulators SGO2 and CTF18 suppress crossovers near centromeres.

Nature plants - 1 Aug 2026

Salinas Gamboa Rigel, Fernandes Joiselle Blanche, Lian Qichao, Singh Dipesh Kumar, Durand Stephanie, Sahu Divyanshu, Capilla-Perez Laia, Lopez Hernan, Kalde Alexandra, Mercier Raphael

Abstract excerpt

Crossovers (COs) ensure proper chromosome segregation during meiosis and generate genetic diversity. COs are non-uniformly distributed along chromosomes and almost universally suppressed in centromere-proximal regions, notably creating an important bottleneck for plant breeding. The mechanism of this CO suppression is still not fully understood, but the chromatin state is a contributing factor. Here we identify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 42498793
DOI: 10.1038/s41477-026-02329-1
PMCID: PMC13481266

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SGO2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.