Article
EMoMiS: A Pipeline for Epitope-based Molecular Mimicry Search in Protein Structures with Applications to SARS-CoV-2
2022-02-07
Abstract excerpt
<h4>Motivation</h4> Epitope-based molecular mimicry occurs when an antibody cross-reacts with two different antigens due to structural and chemical similarities. Molecular mimicry between proteins from two viruses can lead to beneficial cross-protection when the antibodies produced by exposure to one also react with the other. On the other hand, mimicry between a protein from a pathogen and a human protein can le...
Topics
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- Bacterial Infections and Vaccines
- Bacteriophages and microbial interactions
- COVID-19 Clinical Research Studies
- Immunodeficiency and Autoimmune Disorders
- Monoclonal and Polyclonal Antibodies Research
- Pneumonia and Respiratory Infections
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
Identifiers and source
- Literature Corpus work
- 12998661-365e-528b-9e26-82fd430b4a1f
- DOI
- 10.1101/2022.02.05.479274
