Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Benchmarking evolutionary tinkering underlying human–viral molecular mimicry shows multiple host pulmonary–arterial peptides mimicked by SARS-CoV-2

2 Oct 2020

Abstract excerpt

The hand of molecular mimicry in shaping SARS-CoV-2 evolution and immune evasion remains to be deciphered. Here, we report 33 distinct 8-mer/9-mer peptides that are identical between SARS-CoV-2 and the human reference proteome. We benchmark this observation against other viral-human 8-mer/9-mer peptide identity, which suggests generally similar extents of molecular mimicry for SARS-CoV-2 and many other human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to SARS-CoV-2 and COVID-19 Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33024578
DOI: 10.1038/s41420-020-00321-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Benchmarking evolutionary tinkering underlying human–viral molecular mimicry shows multiple host pulmonary–arterial peptides mimicked by SARS-CoV-2PMID 33024578Read ↗

Multi-pronged human protein mimicry by SARS-CoV-2 reveals bifurcating potential for MHC detection and immune evasionSemantic proximity Read ↗

HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronavirusesSemantic proximity Read ↗

A sweep of earth’s virome reveals host-guided viral protein structural mimicry; with implications for human diseaseSemantic proximity Read ↗

Unique Peptide Signatures of SARS-CoV-2 Virus Against Human Proteome Reveal Variants’ Immune Escape and Infectiveness”Semantic proximity Read ↗

HLA‐dependent variation in SARS‐CoV‐2 CD8 + T cell cross‐reactivity with human coronavirusesSemantic proximity Read ↗

SARS-CoV-2 ORF1ab <sup>A1061S</sup> potentiate autoreactive T cell responses via epitope mimicry: an explanation to hepatitis of unknown causeSemantic proximity Read ↗

SARS-CoV-2 selectively mimics a cleavable peptide of human ENaC in a strategic hijack of host proteolytic machinerySemantic proximity Read ↗

Human Identical Sequences of SARS-CoV-2 Promote Clinical Progression of COVID-19 by Upregulating Hyaluronan via NamiRNA-Enhancer NetworkSemantic proximity Read ↗

Unique Peptide Signatures Of SARS-CoV-2 Against Human Proteome Reveal Variants’ Immune Escape And InfectivenessSemantic proximity Read ↗

SARS-CoV-2 strategically mimics proteolytic activation of human ENaCSemantic proximity Read ↗

Identification of potential molecular mimicry in pathogen-host interactionsSemantic proximity Read ↗

Molecular mimicry between SARS-CoV-2 and human proteinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.