Article
Diversity of short linear interaction motifs in SARS-CoV-2 nucleocapsid protein.
mBio - 19 Dec 2023
Schuck Peter, Zhao Huaying
Abstract excerpt
IMPORTANCE: Short linear motifs (SLiMs) are 3-10 amino acid long binding motifs in intrinsically disordered protein regions (IDRs) that serve as ubiquitous protein-protein interaction modules in eukaryotic cells. Through molecular mimicry, viruses hijack these sequence motifs to control host cellular processes. It is thought that the small size of SLiMs and the high mutation frequencies of viral IDRs allow rapid...
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