Article

An Intronic Variant of CHD7 Identified in Autism Patients Interferes With Neuronal Differentiation and Development

2020-08-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Genetic compositions play critical roles in pathogenesis of autism spectrum disorders (ASD). Inherited and <italic>de novo</italic> intronic variants are often seen in patients with ASD. However, the biological significance of intronic variants are difficult to address. Here, we identified a recurrent inherited intronic variant in the <italic>CHD7</italic> gene...

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Literature Corpus work: e738e05f-1926-5fcd-8966-28bc74e479cc
DOI: 10.21203/rs.3.rs-58118/v1

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