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Article

Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity.

Cell - 22 Jul 2021

Williams Drake Winslow, Greenwell-Wild Teresa, Brenchley Laurie, Dutzan Nicolas, Overmiller Andrew, Sawaya Andrew Phillip, Webb Simone, Martin Daniel, Hajishengallis George, Divaris Kimon, Morasso Maria, Haniffa Muzlifah, Moutsopoulos Niki Maria

Abstract excerpt

The oral mucosa remains an understudied barrier tissue. This is a site of rich exposure to antigens and commensals, and a tissue susceptible to one of the most prevalent human inflammatory diseases, periodontitis. To aid in understanding tissue-specific pathophysiology, we compile a single-cell transcriptome atlas of human oral mucosa in healthy individuals and patients with periodontitis. We uncover the complex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34129837
DOI: 10.1016/j.cell.2021.05.013
PMCID: PMC8359928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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