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Complement System and Neutrophil Extracellular Traps Define a Shared Immune Signature in Early- and Late-Onset Preeclampsia

2025-12-10

Abstract excerpt

<h4>Background: </h4> Preeclampsia (PE) is a leading cause of maternal and perinatal morbidity worldwide, yet its mechanisms remain poorly understood. Dysregulated innate im-munity, specifically aberrant complement activation and excessive neutrophil extracel-lular traps (NETs) formation, contributes to endothelial dysfunction and inflammation in preeclampsia. However, the interaction between complement activation...

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Literature Corpus work
e7199911-5609-5f22-b432-6a2aeb7c33ea
DOI
10.20944/preprints202512.0755.v1
Open publication

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