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Article

Complement Activation and Regulation in Preeclamptic Placenta

9 Jul 2014

Abstract excerpt

Preeclampsia (PE) is a common disorder of pregnancy originating in the placenta. We examined whether excessive activation or poor regulation of the complement system at the maternal-fetal interface could contribute to the development of PE. Location and occurrence of complement components and regulators in placentae were analyzed. Cryostat sections of placentae were processed from 7 early-onset PE (diagnosis <34...

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PMID: 25071773
DOI: 10.3389/fimmu.2014.00312

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