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Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia

13 Dec 2024

Abstract excerpt

Background Preeclampsia (PE) is a pregnancy complication characterized by hypertension, proteinuria, endothelial dysfunction, and complement dysregulation. Placenta-derived extracellular vesicles (EVs), necessary in maternal–fetal communication, might contribute to PE pathogenesis. Moreover, neutrophil extracellular traps (NETs) play a pathogenic role in other complement-mediated pathologies, and their...

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Share to Maternal and fetal healthcare
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Pregnancy and preeclampsia studies

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Identifiers

PMID: 39735539
DOI: 10.3389/fimmu.2024.1488127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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