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Article

Complement 5a-mediated trophoblasts dysfunction is involved in the development of pre-eclampsia.

Journal of cellular and molecular medicine - 1 Feb 2018

Ma Yu, Kong Ling-Ran, Ge Qian, Lu Yuan-Yuan, Hong Mo-Na, Zhang Yu, Ruan Cheng-Chao, Gao Ping-Jin

Abstract excerpt

Pre-eclampsia (PE) is a life-threatening multisystem disorder leading to maternal and neonatal mortality and morbidity. Emerging evidence showed that activation of the complement system is implicated in the pathological processes of PE. However, little is known about the detailed cellular and molecular mechanism of complement activation in the development of PE. In this study, we reported that complement 5a (C5a)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29168351
DOI: 10.1111/jcmm.13466
PMCID: PMC5783881

Genes

PIGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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