Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complement and coagulation cascades activation is the main pathophysiological pathway in early-onset severe preeclampsia revealed by maternal proteomics

4 Feb 2021

Abstract excerpt

Abstract Preeclampsia is a pregnancy-specific multisystem disorder and a leading cause of maternal and perinatal morbidity and mortality. The exact pathogenesis of this multifactorial disease remains poorly defined. We applied proteomics analysis on maternal blood samples collected from 14 singleton pregnancies with early-onset severe preeclampsia and 6 uncomplicated pregnancies to investigate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Pregnancy and preeclampsia studies
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33542402
DOI: 10.1038/s41598-021-82733-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complement and coagulation cascades activation is the main pathophysiological pathway in early-onset severe preeclampsia revealed by maternal proteomicsPMID 33542402Read ↗

Maternal plasma proteome profiling of biomarkers and pathogenic mechanisms of early-onset and late-onset preeclampsiaSemantic proximity Read ↗

Early pathways, biomarkers, and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological, and high-dimensional biology studiesSemantic proximity Read ↗

Maternal plasma proteome profiling of biomarkers and pathogenic mechanisms of early-onset and late-onset preeclampsiaSemantic proximity Read ↗

Classification of preeclampsia according to molecular clusters with the goal of achieving personalized preventionSemantic proximity Read ↗

First-Trimester Preeclampsia-Induced Disturbance in Maternal Blood Serum Proteome: A Pilot StudySemantic proximity Read ↗

Complement System and Neutrophil Extracellular Traps Define a Shared Immune Signature in Early- and Late-Onset PreeclampsiaSemantic proximity Read ↗

Molecular Advances in Preeclampsia and HELLP SyndromeSemantic proximity Read ↗

Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of PreeclampsiaSemantic proximity Read ↗

Molecular subclasses of preeclampsia characterized by a longitudinal maternal proteomics study: distinct biomarkers, disease pathways and options for preventionSemantic proximity Read ↗

Late first trimester circulating microparticle proteins predict the risk of preeclampsia < 35 weeks and suggest phenotypic differences among affected cases.Semantic proximity Read ↗

Expression changes of proteins associated with the development of preeclampsia in maternal plasma: A case‐control studySemantic proximity Read ↗

A Review of Candidate Genes and Pathways in Preeclampsia–An Integrated Bioinformatical AnalysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.