Article

The harmonic mean <i>p</i> -value for combining dependent tests

2017-08-02

Abstract excerpt

Analysis of ‘big data’ frequently involves statistical comparison of millions of competing hypotheses to discover hidden processes underlying observed patterns of data, for example in the search for genetic determinants of disease in genome-wide association studies (GWAS). Controlling the family-wise error rate (FWER) is considered the strongest protection against false positives, but makes it difficult to reach t...

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Literature Corpus work: e6f97a64-19fb-56ed-afc0-92bea28f4070
DOI: 10.1101/171751

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