Article

UniGEN-DDI: Computing drug-drug interactions using a unified graph embedding network

2024-10-01

Abstract excerpt

Finding drug-drug interaction is crucial for patient safety and treatment efficacy. Two drugs may show a synergistic effect but may sometimes cause a severe health issue, including lethality. Wet lab studies are often performed to understand such interactions but are limited by cost and time. However, the biochemical data generated can be explored to compute unknown interactions. Here, we developed a computational...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c3174501-1986-5393-bfbe-de4c5e4899d8
DOI: 10.1101/2024.09.30.615812

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

UniGEN-DDI: Computing drug-drug interactions using a unified graph embedding networkDOI 10.1101/2024.09.30.615812Read

GIL-DDI: Multi-View Graph Invariant Learning for Unknown Drug-Drug Interaction PredictionSemantic proximity Read

Mass Enhanced Node Embeddings for Drug RepurposingSemantic proximity Read

MultiGML: Multimodal Graph Machine Learning for Prediction of Adverse Drug EventsSemantic proximity Read

FLONE: fully Lorentz network embedding for inferring novel drug targetsSemantic proximity Read

DPDDI:a Deep Predictor for Drug-Drug InteractionsSemantic proximity Read

Repurposing Drugs for COVID-19 by Graph Convolutional NetworkSemantic proximity Read

D4: Deep Drug-drug interaction Discovery and DemystificationSemantic proximity Read

HeteroRepur: Efficient Modeling of Heterogeneous Disease Graph for Depression Drug Repurposing using Heterogeneous Graph Neural NetworksSemantic proximity Read

DREAM-GNN: Dual-route embedding-aware graph neural networks for drug repositioningSemantic proximity Read

MultiGML: Multimodal Graph Machine Learning for Prediction of Adverse Drug EventsSemantic proximity Read

Leveraging Distributed Biomedical Knowledge Sources to Discover Novel Uses for Known DrugsSemantic proximity Read

<i>MedGraphNet</i> : Leveraging Multi-Relational Graph Neural Networks and Text Knowledge for Biomedical PredictionsSemantic proximity Read