Article

The First Insight into the Epigenetic Fusion Gene Landscape of Acute Myeloid Leukemia

2022-12-12

Abstract excerpt

Epigenetic fusion genes have been defined as the fusion genes produced via cis -splicing of read-through pre-mRNAs of two identical-strand neighbor genes and have been known for decades. However, they need to be adequately investigated. In this study, we analyze RNA-Seq data from 390 AML patients and identify 12,754 EFG isoforms encoded by 5,213 EFGs, one-sixth of all potential EFGs. We characterize 479 EFG isofo...

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Literature Corpus work: e6ccfb93-50e2-550e-96df-1b7d0ef694a3
DOI: 10.1101/2022.12.06.519396

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