Article

Hereditary Fusion Genes Are Associated with the Inheritance of Acute Myeloid Leukemia

2022-11-01

Abstract excerpt

<h4>ABSTRACT</h4> Fusion genes are thought to be somatic and cause cancer, including acute myeloid leukemia (AML). Validating highly-recurrent fusion genes in healthy samples compelled us to systematically study hereditary fusion genes (HFGs). Here, we used curated HFGs to analyze AML fusion genes, and we identified 243 HFGs associated with AML inheritance from 926 potential HFGs. Many HFGs were one-to-many and m...

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Literature Corpus work: bb716fc4-5d09-5dbb-9311-31872cd47937
DOI: 10.1101/2022.10.31.514615

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